The IgM and IgG response to Bordetella pertussis vaccination and infection
نویسندگان
چکیده
منابع مشابه
Regulation of pertussis toxin and lipopolysaccharide levels of Bordetella pertussis 134 in response to modulators
Whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by Bordetella pertussis. Reemerge of pertussis in some highly immunized populations and divergency in gene order among several B. pertussis strains promoted this research to study the change of pertussis toxin (PT) and lipopolysacharide levels in response to the different environments. Th...
متن کاملImmune responses to Bordetella pertussis infection and vaccination.
To assess antibody and cellular immune responses, 156 healthy children were immunized at approximately 18 months of age with acellular diphtheria-tetanus-pertussis vaccine. Changes in antibody responses to filamentous hemagglutinin (FHA) and to pertussis toxin (PT) were similar in pattern, and antibody titers reached values equal to those from patients with convalescent-stage pertussis. The FHA...
متن کاملPertussis Toxin Stimulates IL-17 Production in Response to Bordetella pertussis Infection in Mice
In a mouse model of respiratory tract infection by Bordetella pertussis, bacteria multiply in the airways over the first week and are then cleared over the next 3-4 weeks by the host immune response. Pertussis toxin (PT), a virulence factor secreted exclusively by B. pertussis, promotes bacterial growth in the airways by suppression and modulation of host immune responses. By comparison of wild...
متن کاملregulation of pertussis toxin and lipopolysaccharide levels of bordetella pertussis 134 in response to modulators
whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by bordetella pertussis. reemerge of pertussis in some highly immunized populations and divergency in gene order among several b. pertussis strains promoted this research to study the change of pertussis toxin (pt) and lipopolysacharide levels in response to the different environments. this...
متن کاملThe immunology of bordetella pertussis infection.
Despite the wealth of information on the pathogenesis, virulence and antigenicity of Bordetalla pertussis and the successful development of e#icacious acellular pertussis vaccines, the mechanism of vaccine induced protection against Bordetalla pertussis in man is still poorly understood. Using murine models, we and others have previously reported evidence of the involvement of T cells in protec...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1981
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-14-1-1